پایان نامه تاثیر شدت تمرین برتغییرات الگوی سایتوکاینی (Th1Th2) و تعداد لکوسیت در فوتبالیست ها

فهرست:

فصل اول: طرح پژوهش

     1-1. مقدمه ...............................................................................................................................................2

1-2. بیان مسئله 3

1-3. ضرورت و اهمیت پژوهش 7

1-4. اهداف پژوهش 10

1-4-1. هدف کلی 10

1-4-2. اهداف اختصاصی 10

1-5. سؤالات پژوهش 10

1-6. قلمرو پژوهش ................................................................................................................................11

1-7. تعاریف مفهومی و عملیاتی متغیرها 11

1-7 -1.تعاریف مفهومی 11

1-7-1-1. فعالیت با شدت متوسط 11

1-7-1-2. فعالیت شدید 11

1-7-1-3. اینترفرون گاما 12

1-7-1-4. اینترلوکین-4  12

1-7-1-5. IL-4/IFN-γ 12

1-7-1-6. لکوسیت 12

1-7-2. تعاریف عملیاتی 13

1-7-2-1. فعالیت با شدت متوسط 13

1-7-2-2. فعالیت شدید 13

1-7-2-3. اینترفرون گاما 13

1-7-2-4. اینترلوکین-4 13 

1-7-2-5. لکوسیت 13

عنوان صفحه 

فصل دوم: مبانی نظری و پیشینه پژوهش

2-1.مفاهیم بنیادی 15

2-1-1. سیستم ایمنی 15

2-1-2. اجزا¬ء دستگاه ایمنی 19

2-1-3. سایتوکاین 19

2-1-4. اینترفرون گاما 21

2-1-5. اینترلوکین-4 23

2-1-6 . الگوی سایتوکاینی 24

2-1-7. لکوسیت 27  

2-2. پژوهش¬های پیشین 28

فصل سوم: روش پژوهش

3-1. روش پژوهش 38

3-2. جامعه آماری، روش نمونه¬گیری و نمونه پژوهش 38

3-3. متغییرهای پژوهش 38

3-3-1. متغیر¬های مستقل 38

3-3-2. متغیر¬های وابسته 39

3-4. ابزار و وسایل اندازه¬گیری 39

3-5. روش اندازه¬گیری متغیرهای وابسته 39

3-5-1. شمارش افتراقی سلول¬های خونی 39

3-5-2. اندازه¬گیری سایتوکاین¬ها به روش ELISA 40

3-6. خونگیری و اندازه¬گیری پارامترها 41

3-7. روش اجرای پژوهش 41

3-8. روش¬های تجزیه و تحلیل آماری 44

3-9. ملاحظات اخلاقی 44

عنوان صفحه 

فصل چهارم: یافته¬های پژوهش

4-1. تجزیه و تحلیل توصیفی داده‌ها 46

4-2. بررسی سؤالات پژوهش 47

4-2-1. سؤال اول 47

4-2-2. سؤال دوم 49

4-2-3. سؤال سوم 50

4-2-4. سؤال چهارم 52

فصل پنجم: بحث و نتیجه¬گیری 

5-1. خلاصه پژوهش 55

5-2. بحث و بررسی 57

5-3. نتیجه¬گیری 69

5-4. پیشنهاد¬های پژوهش 70

5-4-1. پیشنهاد¬های کاربردی 70

5-4-2. پیشنهاد¬های پژوهشی 70

  5-5. محدودیت پژوهش 71

فهرست منابع .............................................................................................................................................72

پیوست 

پیوست 1 90

پیوست 2 91

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